Schedule for the Assembly module ================================ Day 1 ~~~~~ - brief overview of the module - assembly exercise - lecture: "Principles and problems of *de novo* genome assembly" - tutorial: exploring De Bruijn graphs - tutorial: assembly with velvet - starting overnight assemblies Day 2 ~~~~~ - basic metrics of the assemblies performed so far - mapping reads back to the velvet assembly - visualisation of mapped reads in IGV - assembly improvement using REAPR - evaluating the other assemblies Day 3 ~~~~~ - comparing assemblies to the reference using Quast - lecture: "Assembly, before and after" - comparative evaluation of assemblies - rounding up: which assembly was best?